Symptoms of Sjogren's syndrome?

summary

Sjogren's syndrome (SS) is a chronic inflammatory autoimmune disease that mainly involves exocrine glands, also known as autoimmune exocrine gland epithelitis or autoimmune exocrine disease. In addition to the salivary gland and lacrimal gland damage and functional decline resulting in dry mouth and dry eyes, there are also other exocrine glands and other organs outside the gland involvement resulting in multi system damage symptoms. There are many kinds of autoantibodies and hyperimmunoglobulinemia in the serum. The disease can be divided into primary and secondary. Symptoms of Sjogren's syndrome? Let's talk about it

Symptoms of Sjogren's syndrome?

Xerostomia due to salivary gland lesions, resulting in the lack of salivary mucin and the following common symptoms: ① most patients complained of xerostomia, serious cases due to oral mucosa, teeth and tongue sticky, so that in the speech need frequent drinking water, into solid food must be accompanied by water or liquid food.

Dry keratoconjunctivitis is caused by the decrease of mucin secreted by lacrimal gland, resulting in dry eyes, foreign body sensation, less tears and other symptoms. Some patients had recurrent suppurative infection of eyelid margin, conjunctivitis, keratitis, etc.

Skin can appear Henoch Schonlein purpura like rash, more common in the lower limbs, for the size of rice, well-defined red papules, pressure does not fade, appear in batches. Each batch lasted for about 10 days, which could subside spontaneously with brown pigmentation.

matters needing attention

(1) Reduce the symptoms of dry mouth, keep the mouth clean, gargle frequently, reduce the possibility of dental caries and oral secondary infection（ 2) Dry cornea and conjunctivitis can be treated with artificial tears to relieve dry eye symptoms and prevent corneal injury（ 3) Non steroidal anti-inflammatory drugs and hydroxychloroquine can be used in patients with muscle and joint pain.