What are the causes of right ventricular outflow tract?

summary

Tetralogy of Fallot is one of the most common congenital heart malformations. 3.6 cases of infants with tetralogy of Fallot are found in every 10000 deliveries, accounting for 12% - 14% of congenital heart diseases, and 50% - 90% of cyanotic heart malformations. In 1988, Fallot made a comprehensive exposition of the four kinds of diseases and clinical features of this disease, so it was later called tetralogy of Fallot. In 1944, Blalock first used the shunt operation of subclavian artery pulmonary anastomosis to reduce cyanosis. What are the causes of right ventricular outflow tract? Let's talk about it

What are the causes of right ventricular outflow tract?

In 1970, van Praagh et al. Thought that the embryonic development disorder of tetralogy was due to the hypoplasia of the distal part of the conus pulmonale or the infundibulum of the right ventricle, without reverse inversion, so the aortic valve remained in the embryonic position, on the right side of the pulmonary valve, and the direction of the septum of the infundibulum, that is, the parietal bundle, should be backward, downward and right during normal development,

In patients with tetralogy, the trend changes to forward, upward and left, and ends at the anterior wall of the conus, so that the right ventricular outflow tract stenosis occurs when the proximal part of the conus is fused with the heart. At the same time, because the septum of the infundibulum is forward and upward, it can not occupy the space between the left anterior superior branch and the right posterior inferior branch of the septal bundle above the ventricular septum

Thus, a huge ventricular septal defect (VSD) is formed in the posterior inferior part of the infundibulum septum, that is, the supraventricular ridge. The hypoplasia of the pulmonary conus causes the aortic opening to move to the right and ride over the VSD.

matters needing attention

It is rich in vitamin C, organic acid, calcium and so on, which is helpful to promote the recovery of septal defect. It is rich in collagen protein, which is one of the necessary nutrients for tissue repair. Therefore, patients with this disease should eat more.