Symptoms of ketosis?

summary

Ketoacidosis is one of the acute complications of diabetes mellitus, which is caused by serious insufficiencies of insulin. When the patient is seriously deficient in insulin, the disorder of glucose metabolism aggravates sharply. At this time, the body can not use glucose, so it has to use fat for energy supply, and the fat combustion is not complete, so the secondary serious disorder of fat metabolism appears: when the fat decomposition accelerates, the ketone body production increases, exceeding the degree of tissue utilization, the ketone body accumulates in the body, making the blood ketone more than 2 mg%, Ketoacidemia occurred. Symptoms of ketosis? Let's talk about it

Symptoms of ketosis?

The symptoms of diabetes are polydipsia, polyuria, fatigue, loss of appetite, nausea and vomiting; Sometimes accompanied by severe abdominal pain, abdominal muscle tension, no rebound pain, like acute abdomen. The patients with severe acidosis are confused and even comatose. Deep and slow breathing, with acetone in the exhalation, similar to the smell of rotten apples. There are obvious signs of dehydration, such as dry skin and mucous membrane, poor elasticity of skin, significant reduction of urine volume, etc.

Ketoacidosis is the first symptom of diabetes in some children. Children with polydipsia, polyuria and other symptoms did not attract the attention of parents. Parents found that children with mental depression, gastrointestinal symptoms, and even delirium to the hospital, is ketoacidosis.

Ketoacidosis continues to worsen and blood pressure drops after treatment. It should be considered that it may be complicated with adult respiratory distress syndrome, cerebral artery thrombosis or disseminated intravascular coagulation.

matters needing attention

In the treatment of ketoacidosis, the use of NaCl solution to correct dehydration and KCl to correct hypokalemia should pay attention to the occurrence of perchloric acidosis. There are many reasons for hyperchlorinated acidosis: for the regeneration of intracellular buffer, bicarbonate consumption in bone and other tissues; When ketone body is excreted from urine, bicarbonate is taken away; The abnormal excretion of hydrogen ions in the distal nephron of the kidney and the dilution of bicarbonate in the extracellular fluid by NaCl and KCl. Hyperchloremia can be corrected by excretion of chloride ions from kidney and regeneration of bicarbonate.