What symptom does pair of medicaments allergy have?

summary

Drug allergy refers to the adverse reactions of patients with specific constitution after using certain drugs. It has nothing to do with the dose of the drug. The incidence rate of drug allergy is not high. There are mainly two forms: one is in the drug at the time of occurrence, known as immediate reaction; The other is latent half an hour or even a few days before it occurs, known as delayed reaction. Mild manifestations included rash, asthma and fever; Severe shock, even life-threatening. What symptom is drug allergy? Let's talk about it.

What symptom does pair of medicaments allergy have?

Urticaria and angioedema type of drug eruption, this kind of drug eruption is more common. The rash is characterized by the occurrence of different sizes of wheal, lasting for a long time. Conscious pruritus can be accompanied by tingling and tenderness. It may be accompanied by local edema around the wind mass. Rash can appear as the only symptom, and also as a symptom of serum sickness like syndrome and anaphylactic shock.

Fixed erythema is the most common drug eruption, accounting for 22% - 44% of drug eruption. The common pathogenic drugs are sulfonamides (long-acting sulfonamides are the first), tetracyclines, antipyretic analgesics and sedatives. Edematous patches are round or oval with clear edges. In severe cases, there are one or more blisters or bullae on the patches. The number of erythema varied from one to several, and the distribution was asymmetric. Can occur in any part, often occurs in the lip and genitalia and other skin mucosa junction, often caused by friction erosion. If relapse, usually still in the original attack, with the previous left pigment spots completely or partially overlap, and often than the previous expansion, increase. Local lesions may be accompanied by pruritus, and patients with extensive lesions may have different degrees of fever. After the erythema subsides, it often leaves purple brown pigment spots, which do not subside for many years, so it has diagnostic value. A small number of edematous erythema without purple, then subsided quickly, and may not leave traces. Individual cases may be accompanied by erythema multiforme like drug eruption, urticaria like drug eruption or measles like erythema.

Severe erythema multiforme drug eruption is a severe bullous erythema multiforme. In addition to skin damage, serious mucosal damage occurs in eyes, mouth and external genitalia, with obvious erosion, exudation and pain. It is often accompanied by chills and high fever. It can also be complicated with bronchitis, pneumonia, pleural effusion and kidney damage. Eye damage can lead to blindness. Children with this type of drug eruption are more common.

matters needing attention

Local treatment: the local treatment and nursing of severe drug eruption patients with skin and mucosal damage is very important, which often becomes the key to the success of treatment. In the early acute stage, a large amount of powder or calamine lotion can be used to protect the skin and reduce inflammation and swelling. If there is exudation, wet compress with normal saline or 3% boric acid solution, change 4-6 times a day. After drying, use 0.5% neomycin and 3% sugar distillate paste, 1-2 times a day.