Polycystic kidney calcification is how to return a responsibility?

summary

The incidence rate of calcification in renal cyst is increasing with the increase of people's nutrition. The proportion of calcification in kidney cyst (kidney stone) in calculus is increasing. Renal calculi mostly occur in young adults, most of them are 21-50 years old. There was no significant difference between the left and right sides, bilateral incidence accounted for 10%. Renal calculi can be located in the pelvis, calyces or ureteropelvic junction, especially in the ureteropelvic junction and lower calyces. The stones can be single or multiple, and the size can vary greatly. The small chestnut grains are large or even silt like, and the large ones can fill the whole renal pelvis and calyces to form staghorn stones or cast stones. Polycystic kidney calcification is how to return a responsibility? Let's talk about it

Polycystic kidney calcification is how to return a responsibility?

The main pathological changes of renal cyst calcification (renal calculi) are direct renal injury, urinary obstruction and secondary infection. The pathological changes of renal calculi are related to the location, size, shape, active area and the degree of obstruction. The direct damage of renal pelvis and calyceal mucosa caused by calculi can cause local epithelial cell abscission, ulcer formation, leukocyte infiltration and interstitial fibrous tissue hyperplasia. The damage of stone to kidney is not determined by the size of stone, but by the degree of urinary obstruction. Large stones do not necessarily cause severe urinary obstruction. Therefore, they do not necessarily cause serious damage to the kidneys.

On the contrary, the small stones embedded in the ureteropelvic junction often cause serious urinary obstruction and lead to hydronephrosis, which leads to renal dysfunction. In severe cases, the renal parenchyma shrinks and even turns the kidney into a water sac. Most renal calculi only cause partial urinary obstruction, and hydronephrosis is not serious. The secondary infection of kidney stone can accelerate the damage of kidney. When the kidney stone has both hydronephrosis and infection, it can become calculous pyonephrosis, which seriously damages the renal function.

The symptoms of renal calculi mainly depend on the size and location of the stone, the degree of obstruction and secondary infection. The stone without obstruction or slight obstruction may be very large and may cause renal damage, but it may be neglected for a long time without significant symptoms. On the contrary, small stones causing acute urinary obstruction can be found early because of severe symptoms.

matters needing attention

The purpose of treatment of renal calculi is not only to relieve the pain and protect the renal function, but also to find and remove the cause as far as possible to prevent the recurrence of calculi. According to each patient's general condition, stone size, stone composition, obstruction, infection, hydronephrosis, renal parenchyma damage and stone recurrence trend, the prevention and treatment plan was formulated.