Symptoms of acidosis

summary

Acidosis refers to the accumulation of acidic substances in blood and tissues. Its essence is the increase of hydrogen ion concentration and the decrease of pH value in blood. Under pathological conditions, when [bhco3] is reduced or [H2CO3] is increased in the body, the [bhco3] / [H2CO3] ratio can be reduced, resulting in the decrease of blood pH value, which is called acidosis. The accumulation of acidic substances in blood and tissues is characterized by the increase of hydrogen ion concentration and the decrease of pH value in blood. Symptoms of acidosis? Let's talk about it

Symptoms of acidosis

Respiratory nerve and muscle dysfunction were found in poliomyelitis, acute infectious multiple neuritis (Guillain Barre syndrome), botulism, myasthenia gravis, hypokalemia or familial periodic paralysis, high spinal cord injury, etc. In severe cases, respiratory muscles may be paralyzed.

Metabolic acidosis can be divided into two categories according to whether the anion gap (Ag) increases or not: metabolic acidosis with increased AG, the plasma [Cl -] level of patients is normal, that is, the normal blood chloride metabolic acidosis often mentioned in the literature. The level of plasma [Cl -] in patients with normal anion gap metabolic acidosis is higher than that in patients with normal anion gap metabolic acidosis.

Extensive lung disease is the most common cause of respiratory acidosis. It includes chronic obstructive pulmonary disease, bronchial asthma, severe interstitial lung disease and so on. These lesions can seriously obstruct alveolar ventilation. The common chest abnormalities that affect respiratory movement are kyphosis, scoliosis, flail chest, ankylosing spondylitis, and cardiopulmonary obesity syndrome.

matters needing attention

In case of dehydration, intravenous infusion of 5% glucose and normal saline was given. The amount of rehydration was determined according to the patient's condition. 5% sodium bicarbonate or 11.2% sodium lactate (except lactic acidosis) can be used as basic drugs. Avoid using sodium salt, can choose 7.28% aminobutanediol (tham) diluted twice after intravenous drip. According to the clinical manifestations and blood gas analysis results, the above drugs can be repeated 1-2 times a day.