The symptoms of mitochondrial disease are freezing

summary

Mitochondrial disease usually occurs in infants, children or early adulthood, presenting a progressive or developmental course. The most common manifestations in infants and young children are stillbirth or stillbirth, progressive encephalopathy, myasthenia, a group of heterogeneous lesions caused by the deficiency of mitochondrial metabolic enzymes caused by genetic deformity, the obstruction of ATP composition, and the lack of energy. The symptom of mitochondrial disease freezes gradually? Let's talk about it

The symptoms of mitochondrial disease are freezing

Mitochondrial myopathy usually starts at the age of 20. The clinical features of mitochondrial myopathy are that skeletal muscles are extremely intolerant of fatigue, and feel tired when they are slightly active. It is often accompanied by muscle soreness and tenderness, and muscle atrophy is rare. It is easy to be misdiagnosed as polymyositis, myasthenia gravis and progressive muscular dystrophy.

Chronic progressive external ophthalmoplegia (CPEO) usually starts in childhood. The first symptom is blepharoptosis, which slowly progresses to complete external ophthalmoplegia, ocular dyskinesia, bilateral external ophthalmoplegia symmetrical involvement, diplopia is not common; Some patients had weakness of pharyngeal muscles and limbs.

Mitochondrial encephalomyopathy with hyperlactemia and stroke like attack (MELAS) syndrome onset before 40 years old, and more in childhood. Sudden stroke like seizures, such as hemiplegia, hemianopia or cortical blindness, recurrent seizures, migraine and vomiting, gradually worsened.

matters needing attention

Keep optimistic and happy. Long term mental tension, anxiety, irritability, pessimism and other emotions, will make the cerebral cortex excitation and inhibition process of imbalance, so we need to maintain a happy mood. Life control, pay attention to rest, work and rest, life orderly, keep optimistic, positive, upward attitude to life, to prevent disease has great help. We should have regular tea and dinner, regular living, no overwork, cheerful mood, and develop good living habits.