What common sense does Rickettsia have?

Update Date: 2023-07-15 Source: Network

summary

Rickettsial disease is a general term for a variety of acute infections caused by some pathogenic microorganisms in Rickettsiales. It is a worldwide or local epidemic with different clinical manifestations. The main transmission media are arthropods, such as ticks, lice, fleas, mites and so on. They can also be caught and bitten by domestic animals, such as cats and dogs. What common sense does Rickettsia have? Let's talk about it

What common sense does Rickettsia have?

Rickettsia often propagates in endothelial cells of small blood vessels and mononuclear phagocyte system after it invades human body, causing cell swelling, proliferation, necrosis, microcirculation disturbance and thrombosis, leading to vascular rupture and necrosis and vasculitis.

And cause perivascular inflammatory infiltration, at this time clinically visible rash (Q fever without rash). Rickettsia can also proliferate in vascular endothelial cells of parenchymal organs (such as liver, spleen, kidney, brain, heart, etc.), leading to cell swelling, proliferation, metabolic disorders, necrosis and interstitial inflammation,

Cause corresponding symptoms. If it invades the brain, there are lymphocytes, polymorphonuclear cells and phagocytes around the blood vessels of the gray matter. This kind of lesion is called "typhus nodule". The incubation period of rickettsial disease is usually within 2-14 days. In addition to the above symptoms, they also showed high fever, headache, rash (Q fever without rash), hepatomegaly and splenomegaly, and some had skin ulcer and eschar.

matters needing attention

Doxycycline, tetracycline, chloramphenicol and so on are quite effective for various rickettsial diseases. For critically ill patients, symptomatic support therapy is very important. When severe patients have respiratory distress, ventilator assisted breathing can be considered. When acute renal insufficiency, dialysis can be considered. At the same time, attention should be paid to correct anemia and coagulation dysfunction.