Is the risk of hyperhomocysteinemia high

summary

From a medical point of view, most people have never heard of the academic names of many diseases, and they do not understand the situation of diseases. However, these diseases will come to patients. Let's talk about the risk of hyperhomocysteinemia.

Is the risk of hyperhomocysteinemia high

First, hyperhomocysteinemia refers to the increase of free and protein bound homocysteine and mixed sulfide in plasma or serum, which is caused by the metabolic disorder of methionine. Homocysteine (Hcy) is an important risk factor for cardiovascular disease. The increased Hcy in the blood can stimulate the vascular wall, cause the damage of the artery, lead to inflammation and the formation of plaque on the wall, and finally cause the obstruction of the heart blood flow. Therefore, hyperhomocysteinemia is an independent and important risk factor for coronary heart disease.

Second: hyperhomocysteinemia is a risk factor for many diseases, especially coronary atherosclerosis, Alzheimer's disease, stroke, venous embolism and other cardiovascular and cerebrovascular diseases. In addition, elevated plasma homocysteine can also lead to neonatal defects and habitual abortion. The mortality of coronary artery disease was positively correlated with the level of plasma total homocysteine.

Third: homocysteine and plasma homocysteine in patients with type 1 and type 2 diabetes mellitus were significantly higher than those in the general population. The level of homocysteine in the serum of diabetic patients with coronary heart disease, diabetic nephropathy and diabetic retinopathy was significantly higher than that of normal people. Elevated homocysteine often causes pregnancy complications, such as abortion, preeclampsia, premature delivery, low birth weight and some neonatal defects. The mechanism is the damage of homocysteine to blood vessels and coagulation mechanism.

matters needing attention

The risk of hyperhomocysteinemia is still very high. If the disease is allowed to develop, patients are prone to some of the above-mentioned risks. For patients, we should pay attention not to let the disease develop and treat it in time.