What harm does miechongling poison have?

summary

Miechongling is a broad-spectrum anthelmintic, which can cure hookworm, Ascaris lumbricoides and trichuriasis. Poisoning is mostly caused by taking a large number of drugs by mistake. If there is heart disease or potassium deficiency, the application of therapeutic dose occasionally has serious reactions, and even has a - s syndrome. If used together with digitalis, chloroquine and antimony, it is easy to cause cardiotoxicity. So what's the harm of miechongling poisoning?

What harm does miechongling poison have?

After poisoning, there are dizziness, headache, nausea, vomiting, abdominal pain, diarrhea, drowsiness and insomnia. Occasionally, epileptic seizures may occur. In severe cases, there may be A-S syndrome. The sick child suddenly loses consciousness, has pale complexion, blue lips, turns up the eyeball and is fixed. The whole body muscles are stiff, limbs twitch, shortness of breath or even stops, arrhythmia, and then heart sounds and pulse disappear, ECG showed ventricular flutter, ventricular fibrillation, ventricular tachycardia or arrest; There are sinus tachycardia and premature ventricular beats, S-T segment changes and obvious U wave in the intermission period. This syndrome often appears 45 minutes to 30 hours after taking medicine.

Excessive intake of miechongling is the main cause of poisoning. If the user has heart disease or potassium deficiency, the application of normal treatment dose may also cause serious adverse reactions, or even cardiogenic cerebral ischemia syndrome. If used together with digitalis, chloroquine and antimony, it can increase the toxicity of drugs and easily lead to cardiotoxicity. The disease is generally caused by excessive consumption, symptoms should be given emesis, gastric lavage and other emergency measures, such as stable condition after routine examination. If the dosage is too large, vomiting, gastric lavage and catharsis should be induced immediately; Intravenous rehydration promotes toxicant excretion and maintains water and electrolyte balance. If there is convulsion, choose quick acting barbiturates, diazepam, chloral hydrate, etc. Patients with ACS or cardiac arrest should be treated in time.

Can lead to as syndrome, as syndrome is cardiogenic cerebral ischemia syndrome, is a group of sudden changes in heart rate caused by acute ischemic attack of clinical syndrome. It refers to the sudden onset of severe and fatal slow and rapid arrhythmia, which leads to a sharp decrease of cardiac output in a short time, resulting in severe cerebral ischemia, loss of consciousness, syncope and other symptoms.

matters needing attention

After intoxication, concentrated saline can be used to induce vomiting, and then a large amount of drinking water can be used to achieve gastric lavage. If large dose is taken, stimulating vomiting and gastric lavage with tannic acid should be used immediately, but do not induce vomiting or irrigate anything to comatose patients, and sulfate should be used for catharsis; Intravenous rehydration can promote the excretion of poisons and maintain the balance of water and electrolyte. Diazepam and chloral hydrate should be used in case of convulsion.