What causes gallstones? Is gender difference also the reason?

summary

Stone is a common disease, most of which are caused by bacterial infection, and the course of disease is long. Most patients can not adhere to the treatment after the disease. This makes the disease is likely to take advantage of the development, the disease continues to delay and repeated, to the patient's body and mind and family have brought great harm. What causes gallstones? Let's talk about it.

What causes gallstones? Is gender difference also the reason?

Reason 1: gender differences: the incidence rate of ultrasound diagnosis in the past few years is about 1:2. The difference of gender ratio is mainly reflected in the incidence of cholesterol stones. There is no significant gender difference in gallbladder bile pigment stone incidence. The high incidence of cholesterol gallstones in women may be related to the decrease of bile flow, the increase of cholesterol secretion in bile, the decrease of total bile acid content and activity, and the effect of progesterone on gallbladder motility and bile stasis.

Reason two: morbidity and diet: eating habits are the main causes of gallstone. The incidence rate of gallstones is higher in those who eat refined food or high cholesterol diet. Because refined carbohydrates increase bile cholesterol saturation. With the improvement of living standards in China, the incidence of gallstones has occupied the main position of cholelithiasis, and cholesterol stones are the main.

Reason three: Gallstone causes the cause of age: most epidemiological studies show that the incidence rate of gallstones increases with age. It may be related to hemolysis or congenital biliary diseases. A survey showed that the incidence of 5 years in 40~69 years old is 4 times that of the low age group. The dividing line between high incidence rate and low incidence rate is 40 years old. Although the reports vary from country to country, the peak age of onset is 40~50 years old.

matters needing attention

Clinical and epidemiological studies show that obesity is an important risk factor for gallstone cholesterol gallstones, and obesity incidence rate is 3 times that of normal weight people. Obese people are more likely to suffer from gallstones because of the absolute increase of cholesterol synthesis, or the relative increase of bile acid and phospholipid, which makes cholesterol supersaturated.