What medicine does esophagus countercurrent take?

summary

Symptoms of GERD include chest burning, burping, nausea, vomiting, chest pain, and acid reflux. In addition, eating too fast or too full can also cause gastroesophageal reflux disease. Typical heartburn symptoms usually occur after meals, especially when lying down or exerting on the abdomen.

What medicine does esophagus countercurrent take?

H2 receptor antagonists (H2RA) such as cimetidine, ranitidine, famotidine, etc. H2RA can reduce the 24-hour gastric acid secretion by 50% - 70%, but it can not effectively inhibit the gastric acid secretion stimulated by eating. Therefore, it is suitable for patients with mild to moderate peptic ulcer. It can be used according to the conventional dosage for the treatment of peptic ulcer, but should be taken in batches. Increasing the dosage can improve the curative effect, but increase the adverse reactions. The treatment course is 8-12 weeks.

These drugs can increase the pressure of LES, improve the function of esophageal peristalsis and promote gastric emptying, so as to reduce the reflux of gastric contents and the exposure time in esophagus. Although there are many kinds of these drugs, cisapride is recommended as the treatment of this disease according to the results of a large number of clinical studies. The efficacy of cisapride is similar to that of H2RA, and it is also suitable for patients with mild and moderate symptoms. The common dosage is 5-15mg each time, 3-4 times a day, and the course of treatment is 8-12 weeks.

Proton pump inhibitors (PPI) include omeprazole, pantoprazole, etc. These drugs have strong acid inhibitory effect, so the curative effect of this disease is better than H2RA or cisapride, especially suitable for patients with severe symptoms and severe esophagitis. The treatment course is 8-12 weeks. The dosage of cisapride can be doubled or used together with cisapride.

matters needing attention

General treatment diet should be a small number of meals, not too full; Avoid smoking, alcohol, coffee, chocolate, sour food and excessive fat; Avoid lying flat after meals; When lying, the head of the bed should be raised by 20 ~ 30cm to make the patient feel comfortable. Mattress Genie can be used to assist, and the belt should not be too tight to avoid various situations that cause excessive abdominal pressure.