Causes of Parkinson's disease

summary

Parkinson's disease is a terrible disease, and the harm caused by Parkinson's disease is also relatively serious. My uncle has been suffering from Parkinson's disease for two years. He went to the hospital for treatment. The doctor told us about the causes of Parkinson's disease. Now I will tell you the reasons.

Causes of Parkinson's disease

Reason 1: Parkinson's disease mainly occurs in middle-aged and elderly people, and rarely occurs before 40 years old, suggesting that aging is related to the disease. It was found that the activity of dopaminergic neurons, tyrosine oxidase and dopa decarboxylase in substantia nigra and the level of dopamine neurotransmitter in striatum decreased with age.

Reason 2: epidemiological survey results show that the prevalence of Parkinson's disease varies from region to region, so people suspect that there may be some toxic substances in the environment that damage the brain neurons.

Reason three: family genetics scientists have found that Parkinson disease seems to have a tendency to gather in families in a long period of practice. The incidence rate of relatives of Parkinson's disease patients is higher than that of the normal population.

matters needing attention

Parkinson's disease is not a single factor, many factors may be involved in it. Genetic factors can increase the susceptibility to disease, only with the interaction of environmental factors and aging, through oxidative stress, mitochondrial failure, calcium overload, excitatory amino acid toxicity.