Medication for epilepsy in children

Update Date: Source: Network

summary

I've been suffering from epilepsy for more than a year. Every attack will appear in a trance, limbs twitch, completely unable to control their own body, but now through the recovery of health, so many students to consult the treatment of children with epilepsy medication.

Medication for epilepsy in children

Drug 1: phenytoin sodium: it is effective for generalized tonic clonic seizures and partial seizures, but it can aggravate absence and myoclonic seizures. Gastrointestinal absorption is slow, metabolic enzymes can be saturated, after saturation, increase a small dose is the most toxic dose, children are not easy to find toxic and side effects, so infants and children should not take, adults should be careful when dosage. Usually, adults can take it once a day and children can take it twice a day.

Drug 2: carbamazepine: it is the first choice for partial seizures. It is better than other antiepileptic drugs in the treatment of complex fractional seizures. It also has better effect on secondary generalized tonic clonic seizures, but it can aggravate absence and myoclonic seizures. Due to the self induction of liver enzymes, the clearance rate was low at the beginning of treatment, and gradually increased to the therapeutic dose one week later. After 3-4 weeks of treatment, the same effect can be maintained only by increasing the dose.

Drug 3: valproic acid: a broad-spectrum antiepileptic drug, is the first choice for generalized seizures, especially generalized tonic clonic seizures combined with typical absence seizures, also used for partial seizures. Gastrointestinal absorption is fast. Phenobarbital: it is often used as the first choice drug for children with epilepsy. It has a broad spectrum and quick onset. It has good curative effect on generalized tonic clonic seizures. It is also used for simple and complex partial seizures and has preventive effect on febrile convulsions. It can be used for acute brain damage with epilepsy or status epilepticus.

matters needing attention

From the beginning of premenstrual period, the level of progesterone decreased, and the ratio of estrogen and progesterone gradually increased, so this stage is the peak of attack. 10 days after menstruation, progesterone reaches its peak underwater, and the ratio of estrogen and progesterone decreases, so this stage is the low peak stage of onset. The metabolism of antiepileptic drugs also changes with the rest of menstruation. During menstruation, the patient should keep a good mood and not eat cold food.