Does basophil high have relation with leukaemia?
summary
Does basophil high have relation with leukaemia? A: not necessarily. Basophils are one of the five types of leukocytes. The normal number of basophils is (0-0.1) × 109 / L, accounting for 0-1% of the total white blood cells. Because basophilia is a clinical abnormal phenomenon in laboratory examination, there are many reasons for this phenomenon, many related diseases can appear basophilia, to determine whether it is related to leukemia, we need to identify various related diseases, we must carry out relevant examination, such as detailed physical examination, blood routine, liver and kidney function Bone marrow puncture and other examinations. The human body is a very precise "instrument". If there is some abnormal situation, there will be corresponding diseases. Only when we have a comprehensive understanding can we understand the truth.
Does basophil high have relation with leukaemia?
1. The causes of basophilia include allergic diseases: allergic enteritis, allergic reactions caused by drugs and food; Rheumatoid arthritis, etc; Blood diseases: chronic myeloid leukemia, basophil leukemia, bone marrow fibrosis and other diseases; Malignant tumor: mostly seen in metastatic tumor, the mechanism is unknown; Other: diabetes, infectious diseases: smallpox, chickenpox, etc.
2. The diagnosis basis of CML is as follows: chronic phase: fatigue, low fever, hyperhidrosis, weight loss, splenomegaly; Hemogram: WBC increased, eosinophilic basophil increased; Myelogram: proliferation was active, eosinophilic basophil increased; Acceleration period: fever, weakness, weight loss, bone pain, splenomegaly. The percentage of basophils in peripheral blood was more than 20%. Blastic phase: in the end stage of CML, the percentage of PBG + PLG > 30%. Bone marrow: blasts + lymphoblasts + monocytes > 20%.
3. The diagnosis basis of basophil leukemia is divided into two types; 1. Acute anemia, fever, fatigue, weakness, general malaise, diarrhea, bleeding, etc. 2. The early hemogram and bone marrow of chronic myeloid leukemia are similar to those of chronic myeloid leukemia, and the late stage is similar to CML. Diagnosis basis: the number of basophils in blood and bone marrow was more than 30%
matters needing attention
Check their own clinical manifestations of leukemia: such as fever, anemia, infection, lymphadenopathy, etc; 2. To the regular hospital to improve blood routine, bone marrow puncture and other related examination; 3. Relax.