What is cerebrovascular sclerosis

summary

My grandfather had suffered from cerebral arteriosclerosis before, mainly because of his unstable blood pressure, sometimes caused by low blood pressure. This kind of disease is very harmful and needs to be treated as soon as possible. Now let's see what is cerebrovascular sclerosis.

What is cerebrovascular sclerosis

First of all, cerebral arteriosclerosis refers to a series of pathological changes caused by cerebral vascular diffuse atherosclerosis, lumen stenosis and small vessel occlusion resulting in the decrease of cerebral blood supply. This disease is a common disease of central nervous system. Its clinical characteristics are progressive cerebral dysfunction, cerebral infarction, cerebral hemorrhage and diffuse brain damage.

Secondly, spontaneous cerebral hemorrhage accounts for 10-20% of all stroke, with high mortality and disability rate. Blood stagnation and shear stress can cause intimal damage; chylous microthrombosis, hyperlipidemia and platelet aggregation can form microthrombosis, which can increase intra-arterial pressure, damage the compensatory ability of vascular smooth muscle, dilate blood vessels, increase intimal permeability, make macromolecular low-density lipoprotein and blood oar components infiltrate under the intima, macrophage and smooth muscle derived from monocytes The cells replenish the damaged intima, where the intima is proliferated, aggregated fatty esters, and become foam cells, and then die. In patients with cerebral atherosclerosis, extracellular cholesterol is deposited in the intima and forms plaques.

Finally, it leads to ischemia, vitreous degeneration and necrosis of vascular wall, and then to stenosis, occlusion or rupture of vascular wall. The earliest change of arteriosclerosis is the strip lipid accumulation in the vascular intima, and the macrophage phagocytosis is under the intima under microscope. This change is reversible in the early stage.

matters needing attention

Limit the intake of high cholesterol and high fat diet to reduce the deposition of lipids in blood vessels. Eat more alkaline things, can avoid cardiovascular and cerebrovascular diseases, for the improvement of the disease also has a good effect.