How to treat dwarfism

summary

Dwarfism is a kind of disease with abnormal physical development caused by insufficient secretion of growth hormone. Many people will actively take various ways to treat dwarfism after they find that they have dwarfism. This article will introduce the methods of treating dwarfism.

How to treat dwarfism

Treatment one: growth hormone. The younger the application age of growth hormone, the better. The dosage of recombinant DNA growth hormone (hGH) is 0.7u/kg per week. The injection effect is better when the dosage is divided into daily injection for 2 weeks, stopping for 2 weeks, reducing after several months, and maintaining for 1-2 years, or even 5-6 years or longer. It can also be injected subcutaneously with hGH 0.12u/kg once a day for one year. In the initial stage of use, the patient's growth rate will be significantly accelerated, while his height and weight will increase rapidly, but the changes of epiphysis and sexual characteristics are not significant. Since 1985, GHRH has been synthesized by bioengineering. Its usage is ghrh1-29 30 ～ 60 μ g / kg and HGH 0.1u/kg. It is injected subcutaneously into abdominal wall 30 minutes before going to bed every night. After 6 months of treatment, 40% ～ 80% of patients respond to the stimulation of GHRH.

Treatment 2: androgen. In the treatment of hGH, androgen should not be used at the same time or early to avoid early bone fusion. If the curative effect of GH is not good, we can use synthetic steroid hormone, such as norone propionate, but we must master that the bone age is obviously less than the age. Generally, the bone age is more than 5 years behind. It's better to start the application when the diagnosis is clear from 8 to 12 years old. When the diagnosis is suspicious from 14 years old, the dosage is 1 to 1.5mg/kg, once every two weeks, intramuscular injection, half a year as a course of treatment. If the difference between bone age and age is less than 3 years, the drug is not used temporarily. After treatment, the height can be increased by about 10 cm every year, the appetite is increased, the weight is increased, the muscle is developed, the physical strength is strong, and the external genitalia is developed. The effect of male is better than that of female.

Treatment 3: human chorionic gonadotropin (hCG). It is generally believed that it is better to start from the age of sexual development. The dosage is 500-1000u, subcutaneous injection, twice a week, half a year as a course of treatment, or 1000u every other day, intramuscular injection, 2 weeks later, it is 500U, twice a week, 3-4 months as a course of treatment, which can achieve certain curative effect and stimulate the development of gonad and secondary sexual characteristics.

matters needing attention

Once people find that they have dwarfism at ordinary times, they can take the above measures for treatment, and women should avoid the risk factors that can cause the disease during pregnancy, including keeping away from smoke, alcohol, drugs, radiation, pesticides, noise, volatile harmful gases, toxic and harmful heavy metals, etc.