How is creatinine low to return a responsibility

summary

In the detection of human kidney function, creatinine is the most common test items and indicators in the detection process. Therefore, for the common low creatinine, patients need to find the corresponding reasons. Therefore, this paper will share the reasons for low creatinine as follows.

How is creatinine low to return a responsibility

First, after the kidney is invaded by various causes, the damaged renal intrinsic cells undergo phenotypic transformation, stimulating the fibroblasts in the kidney to transform into myofibroblasts, and at the same time invading and stimulating the inherent normal kidney Tissue, the same lesions, thus forming a kidney from the point to the surface, from local to the whole, expand the spread of excitation process, so as to enter the organic damage period (that is, renal function damage period).

Second: at this time, due to the continuous damage of the kidney, the function of excreting waste is reduced, resulting in the accumulation of creatinine and other toxins in the body, resulting in the increase of blood creatinine and urea nitrogen, the decrease of urine creatinine, and the decrease of double kidney filtration rate.

Third: in clinical practice, there are many factors that can cause low creatinine in the human body, such as anemia, creatinine malnutrition, muscle atrophy, leukemia, diabetes insipidus and other diseases. In the creatinine value, there is a test data value called urea nitrogen value, but this urea nitrogen value is easily affected by many other factors, so it can not simply reflect the renal function.

matters needing attention

After understanding the causes of low creatinine, patients should control the protein intake in diet.