Staging symptoms of chronic renal failure?

summary

Chronic renal failure (CRF) is a clinical syndrome composed of a series of symptoms and metabolic disorders caused by a variety of kidney diseases leading to progressive and irreversible decline of renal function until functional loss. In life, if suffering from chronic renal failure, then we have to face the cruel disease for a long time. Usually, the course of chronic renal failure can be divided into three stages. Staging symptoms of chronic renal failure? Let's talk about it

Staging symptoms of chronic renal failure?

Stage I: renal function compensation stage: in this period, the glomerular filtration rate of patients will be hundreds of times lower than that of normal people, and the renal function of patients has obviously deteriorated. At this stage, the nephron decreased by 20% - 25%. Although the renal reserve capacity has been lost, the ability of excreting metabolites, regulating water, electrolyte and acid-base balance is still good, so there is no special clinical manifestation. The blood muscle enzymes and blood urea nitrogen are usually normal or sometimes slightly increased.

Phase II: azotemia: at this time, the glomerular filtration rate of patients will further decline, the nephron will be reduced by more than half, the renal concentration function will also appear obvious obstacles, nocturia or polyuria, anemia of different degrees, often azotemia, serum creatinine, urea nitrogen increase. Clinical can have fatigue, loss of appetite, nausea and mild discomfort and so on. In this period, if the protection of renal function or extra load of the body is ignored, there will be severe vomiting, diarrhea and insufficient blood volume. If there is infection or the use of nephrotoxic drugs, it can cause rapid decline of renal function and failure.

Stage III: renal failure stage: during this period, the patient is actually under the threat of uremia. It can also be said that this is the early stage of secondary uremia. During this period, when the glomerular filtration rate is reduced to 10-15ml per minute, the nephron is reduced by about 70% - 90%. The renal function is seriously damaged, and the body's metabolism, water electrolyte and acid-base balance cannot be maintained. * it is impossible to maintain the stable environment of the machine, resulting in a marked increase in serum creatinine and urea nitrogen, dysfunction of urine concentration and dilution, acidosis, retention of water and sodium, and imbalance of low calcium, high phosphorus and high potassium.

matters needing attention

With the continuous development of patients with chronic renal failure, patients will gradually fall into the harm of uremia, so in life, if we find the condition of renal failure, we should make timely diagnosis and treatment, do not lead to delay the disease.