What symptom can vitamin C poison?

summary

Large dose can cause abdominal distention, skin rash, excessive gastric acid or urinary stones, serious cases can cause hemolysis, even fatal. If a large dose is taken for a long time and the drug is stopped suddenly, scurvy symptoms may appear. What symptom can vitamin C poison? Let's talk about it.

What symptom can vitamin C poison?

1. Vitamin A (1) due to the individual differences in the sensitivity of children to vitamin A and the different storage of vitamin A in the liver, the poisoning dose of acute type children may have great differences. Generally, injection of 300 000 IU of vitamin A can produce toxic symptoms within a few days. The manifestations were anorexia, irritability or drowsiness, vomiting, anterior fontanelle swelling, head circumference enlargement, cranial cleft, papilledema, etc. Elevated intracranial pressure is common in acute type, which seems to be caused by increased volume of cerebrospinal fluid or malabsorption（ 2) The dosage of chronic vitamin A can reach tens of thousands of units per day. If infants and young children take vitamin a 1500 IU per kilogram of body weight per day, they may have toxic symptoms after a few days. Early irritability, loss of appetite, low fever, hyperhidrosis, alopecia, after a typical bone pain symptoms, metastatic pain, can be accompanied by soft tissue swelling, tenderness without red, hot signs, to long bones and limbs bone more common, because the long bone involved epiphysis embedded, can lead to short body material. Some cases had swelling and pain in the temporal and occipital region, which could be misdiagnosed as craniomalacia. Symptoms of increased intracranial pressure, such as headache, vomiting, wide and protruding anterior fontanel, skull suture separation, binocular esotropia, nystagmus, diplopia and so on, are the other characteristics of the disease, but they are rare in acute type. In addition, there are pruritus, desquamation, rash, chapped lips, dry hair, hepatosplenomegaly, abdominal pain, myalgia, bleeding, kidney disease, and aplastic anemia with reduced white blood cell count. The alkaline phosphatase in blood increased.

2. Vitamin D vitamin D is the most easily toxic of all vitamins. Its poisoning symptoms and signs mainly include: hypercalcemia, myasthenia, apathy, headache, anorexia, nausea, vomiting, bone pain, ectopic calcification, proteinuria, hypertension and arrhythmia. Chronic hypercalcemia can lead to systemic vascular calcification. Renal calcification and rapid decline of renal function. Taking 600001 U (1.25 mg) per day can lead to poisoning symptoms.

3. Long term use of large dose of vitamin E is not easy to cause poisoning. However, taking 300-800 mg of vitamin E every day will lead to poisoning symptoms such as muscle weakness, fatigue, headache and nausea. Excessive vitamin E may also cause massive bleeding. For people taking drugs that reduce blood coagulation (such as aspirin), excessive intake of vitamin E is more dangerous.

matters needing attention

Some people advocate taking a large dose of vitamin C for a long time to prevent cold and cancer, and reduce blood lipid, but we should strictly prevent overdose poisoning. It has been reported that diarrhea can occur when taking 1 gram daily. Taking 4 g at a time can cause uric acid and urine. Long term high-dose administration can cause oxalate calculus in some patients and hemolysis in patients with glucose-6-phosphate dehydrogenase (G-6-PD) deficiency. Pregnant women take large doses of vitamin C, can make the baby scurvy.