What are the causes of hepatitis C recurrence

summary

During this period of time, I feel very tired and don't want to do anything. I just want to sleep in bed. I always get up in a daze every morning. I feel dizzy and have a bad appetite. I feel haggard. When I go to the hospital, it turns out that I have hepatitis C. Now let's talk about the causes of hepatitis C recurrence.

What are the causes of hepatitis C recurrence

The first reason is. Direct killing effect of HCV: replication of HCV in hepatocytes interferes with the synthesis of intracellular macromolecules, increases the permeability of lysosomal membrane and causes cytopathy. In addition, some HCV envelope proteins are toxic to the host cells when expressed in vitro. 　　

The second reason is: host immune factors: it has been confirmed that there are HCV specific cytotoxic lymphocytes CD8 + T cells in liver tissue, which can attack HCV infected liver cells. In addition, cytokines secreted by CD4 + Th cells after being sensitized can help to eliminate HCV, but also lead to immune damage. 　　

The third reason is: autoimmunity: HCV infection is often accompanied by autoimmune changes, such as bile duct pathological damage is similar to autoimmune hepatitis. Many kinds of autoantibodies, such as antinuclear antibody, anti smooth muscle antibody, anti single strand DNA antibody, anti mitochondrial antibody, can be detected in the serum of patients with autoimmune diseases. 　　

matters needing attention

It is difficult to say the recurrence rate of hepatitis C. The recurrence rate of each patient is different. The recurrence rate of hepatitis C is related to many factors, so there is no definite number. At the same time, in order to avoid recurrence, patients with hepatitis C should do a good job in treatment and maintenance.