Does nasopharyngeal carcinoma mandible necrosis symptom?

summary

Nasal, ear, eye, oral symptoms. Most of the patients (> 98%) will have the symptoms of the above-mentioned parts due to the invasion and expansion of primary cancer and surface ulcer infection. The time and sequence of clinical symptoms are determined according to the location and size of the tumor.

Does nasopharyngeal carcinoma mandible necrosis symptom?

Cancer is located at the top of the nasopharynx, the first appearance of blood in the nose, blood can spit out from the mouth, accompanied by nasal congestion and other diseases; The tumor is located in the pharyngeal recess. In the early stage, it often has tinnitus, ear closure, hearing loss and so on. It is easy to be misdiagnosed as catarrhal exudative otitis media or suppurative otitis media; The tumor infiltrated into the eye, manifested as unilateral exophthalmos, diplopia, eye movement disorders, etc; The tumor infiltrated the medial pterygoid muscle and presented with difficulty in opening the mouth. When the hypoglossal nerve was involved, the movement of the lingual muscle was impaired and the tongue deviated to the healthy side.

Cranial nerve symptoms: nasopharyngeal carcinoma infiltrates and expands upward, which may involve cranial nerves and cause corresponding symptoms. Clinically, cranial nerves V and VI are the first to be involved. With tumor expansion, cranial nerves III, IV, IX and X are also damaged, while cranial nerves I and II are located in the anterior part of the skull, while cranial nerves VII and VIII are located in the petrous part of the temporal bone. The upper cranial nerves were involved, showing loss of function. Headache is often a sign of the tumor expanding into the brain. Headache is a persistent and fixed severe migraine, mostly located in the trigeminal sensory distribution area, the nature can be distending pain, muggy pain or tight pain.

Neck signs: mainly refers to the mass caused by cervical lymph node metastasis. Clinically, painless mass in neck can be the first symptom, even the only symptom. The mass first appeared on one side and enlarged rapidly, then involved the opposite side of neck.

matters needing attention

Distant metastasis symptoms: the most common sites of NPC metastasis are bone, lung and liver. Bone metastases are common in pelvis, spine and limbs. Clinical observation showed that with the enlargement of cervical lymph nodes, the chance of distant metastasis increased significantly. The rate of distant metastasis was 4.8% ~ 27%, and the rate of autopsy was as high as 76%.