Symptoms of propylene poisoning?

summary

Acrylonitrilc pnisnnin} is a kind of high toxicity. It can release cyanogen ions in the body, inhibit cytochrome oxidase and cause tissue hypoxia. Its molecule itself is also toxic. The symptoms of acute propylene lung poisoning are similar to those of hydrocyanic acid. Mild cases have dizziness, headache, fatigue, nausea, vomiting, numbness of hands and feet, hazy consciousness, Ziwei, etc. severe cases have paroxysmal tetanic convulsions and coma of limbs, which may lead to secondary respiratory and circulatory failure. When the skin is contaminated, local erythema, papules and water scars appear.

Symptoms of propylene poisoning?

Subacute poisoning: close contact with a large number of people can lead to subacute onset, somnolence and cerebellar dysfunction, manifested as horizontal nystagmus and vague speech. Instability of finger, nose, heel, knee and tibia test, rotation movement disorder, gait instability, etc. Two weeks later, the patient developed sensorimotor polyneuropathy with numbness, pain and weakness of lower limbs. Tuning fork vibration sense and Achilles tendon reflex decreased, which has early diagnostic value. Neuroelectromyography showed that the distal sensory potential was significantly decreased, with neurogenic damage and more spontaneous denervation potential.

Chronic poisoning: after exposure to low concentration for several months and years, headache, dizziness, fatigue, drowsiness, finger pain, numbness, often accompanied by redness, desquamation and sweating of palms and feet. Further weakness, muscle pain. Gait faltered, easy to fall forward, nervous system examination, deep reflex weakened or disappeared, tuning fork vibration sense and position sense decreased, eyes closed, difficult to stand test positive, etc. The results of neuroelectromyography were similar to those of subacute poisoning; EEG may be mildly abnormal.

In the production process of acrylamide, or used in resin synthesis, adhesives, underground construction, soil improvement, paint, paper and other industries, there are opportunities to contact this product. There are three forms of contact with acrylamide: oral, respiratory inhalation and skin contact. Acrylamide is distributed in body fluids after inhalation. Water is the most important pollutant. Non occupational exposure to acrylamide mainly comes from drinking water and food contaminated by acrylamide. Poisoning can be caused by poor pre care.

matters needing attention

Acrylamide is white crystalline powder, soluble in water, and easy to polymerize with ethanol, ether and acetone; It can be hydrolyzed to acrylic acid in acid-base environment. Acrylamide is a kind of moderate toxicity, which can be absorbed through skin and respiratory tract. It can accumulate in the body and mainly affect the nervous system. It can cause fatigue, pain, numbness, ataxia and even muscle atrophy. Acrylamide in the body needs to accumulate to a certain dose before onset, so acute poisoning is very rare, mainly manifested as delayed toxicity, causing subacute and chronic poisoning. Acrylamide can also stimulate eyes and skin. The incidence rate is mostly acute and subtropical.