What is thalassemia

summary

Most people will have anemia. We often hear about thalassemia, but most people don't know about it. Let's introduce what thalassemia is.

What is thalassemia

First, α - globulin production disorders anemia can be born anemia, clinical manifestations of mild to moderate chronic anemia, accompanied by jaundice, hepatosplenomegaly. Secondary infection and taking oxidant drugs can aggravate the instability of HBH and promote hemolysis. Pregnancy may aggravate anemia. In general, the development of patients is not affected, and the bone changes are not obvious.

Second, the children with homozygous (β 0) globulin production disorder anemia were normal at birth. A few months after birth, HbF was gradually replaced by HbA (α 2 β 2), and the children developed anemia, which was progressive aggravation, including fever, anorexia, diarrhea, jaundice, liver and spleen swelling. At the age of 3-4 years old, they showed growth retardation, mental depression, expressionless face and weakness. Bone marrow hemopoietic compensatory hyperplasia widens the bone marrow cavity and thins the bone cortex, leading to forehead and top bulge, head enlargement, cheek bulge, bridge of nose collapse, maxillary and teeth protrusion, forming a special face. The patient developed chronic ulcer of lower limbs. The earlier the onset, the more severe the symptoms.

Third, heterozygous (β) thalassemia, which is also known as resting or miniature β - thalassemia, is mainly due to the fact that most of the patients have no anemia or other symptoms, and most of them will be found in the census or family survey. Blood examination may find a small number of target red blood cells, the osmotic fragility of red blood cells is slightly decreased, and HBA2 is slightly increased. A few patients may have anemia, especially when combined with pregnancy or secondary infection, the performance of mild to moderate anemia, jaundice, mild splenomegaly.

matters needing attention

If anemia, usually pay more attention to rest, can not stay up late, you can eat more blood food, such as longan, jujube and so on.