What is hyperhomocysteinemia

summary

Blood is the river in the human body. Some people's blood is not very good. A relative in his hometown has a blood problem, which is hyperhomocysteinemia. Let's talk about the relevant knowledge of hyperhomocysteinemia.

What is hyperhomocysteinemia

First of all, hyperhomocysteinemia refers to the increase of free and protein bound homocysteine and mixed sulfide in plasma or serum, which is caused by the metabolic disorder of methionine. Homocysteine (Hcy) is an important risk factor for cardiovascular disease. The increased Hcy in the blood can stimulate the vascular wall, cause the damage of the artery, lead to inflammation and the formation of plaque on the wall, and finally cause the obstruction of the heart blood flow. Therefore, hyperhomocysteinemia is an independent and important risk factor for coronary heart disease. This has a great impact on the body, many people are not actively treated, leading to the deterioration of the body.

Secondly, methionine metabolic disorder can lead to hyperhomocysteinemia, which is caused by genetic and environmental factors. Three key enzymes, methylenetetrahydrofolate reductase, cystathionine condensase and methionine synthetase, were deficient or their activities decreased due to genetic factors. Environmental nutritional factors refer to the high content of methionine in high animal protein diet, excessive intake is easy to cause the increase of Hcy level, and the lack of metabolic cofactors such as folic acid, vitamin B6 and B12. These factors are essential factors in the metabolic reaction of homocysteine, which can lead to the occurrence of Hyperhomocysteinemia.

Finally, hyperhomocysteinemia is a risk factor for many diseases, especially coronary atherosclerosis, Alzheimer's disease, stroke, venous embolism and other cardiovascular and cerebrovascular diseases. In addition, elevated plasma homocysteine can also lead to neonatal defects and habitual abortion.

matters needing attention

Supplement of vitamin B6, vitamin B12 and folic acid can reduce plasma homocysteine level. On the other hand, we should limit the intake of methionine and reduce the intake of animal protein. To eat more fresh fruits and vegetables, and to correct their attitude, to let their body slowly healthy.