How does the symptom of short stature treat

summary

Dwarfism refers to children whose height is lower than the two standard deviations (- 2sd, SD) of the average height of children of the same gender, age and race, and whose annual growth rate is less than 5cm. The growth rate of children was less than 7 cm / year before 3 years old; ② It is less than 5 cm / year from the age of 3 to adolescence; ③ Puberty is less than 6 cm / year. How is the symptom of short stature treated? Let's talk about it

How does the symptom of short stature treat

Recombinant human growth hormone (rhGH) replacement therapy has been widely used. At present, most of them are given subcutaneous injection of 0.1 U / (kg · d) before going to bed, 6-7 times a week. The treatment should continue until the epiphysis is healed. The younger the age is, the better the effect is. The effect is the best in the first year. The annual growth rate can reach more than 10 cm, and then the growth rate gradually decreases. Thyroxine deficiency may occur in the course of treatment with rhGH. Therefore, thyroid function should be monitored. If there is a deficiency, thyroxine should be added at the same time.

Oral sex hormone protein anabolic steroids are: 1) fluroxyprogesterone 2.5mg/m2 per day, 2) oxymethylprednisolone 0.1-0.25mg/kg per day, 3) pyrazolone 0.05mg/kg per day. They are androgen derivatives. They have strong anabolic effect and weak androgen effect. They have side effects of accelerating bone maturation and masculinization. Therefore, it is necessary to closely observe bone development. At present, norone propionate is rarely used.

Growth promoting hormone releasing hormone (GHRH) is known to lack hypothalamic GH, so the application of GHRH can be effective for ghnd, but not for pituitary GH deficiency. Generally, the dosage is 8-30ug / kg per day, subcutaneous injection once a day in the morning and evening or continuous injection with 24h subcutaneous micro pump.

matters needing attention

For simple short children, special attention should be paid to the following points in maintenance, such as ensuring adequate sleep, strengthening physical exercise and outdoor sunlight, so as to promote their growth. At the same time, we should pay special attention to the balanced nutrition, but we should not give the baby a lot of supplements because the baby is short, because it may contain hormones and so on, which may stimulate the early development of children, resulting in short.