What reason is granulation oedema?

Update Date: 2022-12-05 Source: Network

summary

Granuloma is a well-defined nodular lesion formed by limited infiltration and proliferation of macrophages and their evolving cells. The essence of granuloma is inflammation caused by delayed hypersensitivity. Macrophages and epithelioid cells play an important role in immune response. Therefore, granuloma can be defined as the aggregation of macrophages and their derived cells (such as dermoid cells, multinucleated giant cells) with or without the presence of other inflammatory cells. What reason is granulation oedema? Let's talk about it

What reason is granulation oedema?

1. The tumor like theory is similar to that of reticular cell sarcoma or lymphoma, with neoplastic proliferation of heteromorphic cells and mitotic phase, without necrotic blood vessels and multinucleated giant cells. This disease is limited to the nose and respiratory tract. In the late stage, the same lesions can be seen in all parts of the body, such as viscera, lymph nodes and bone marrow. Therefore, it is very similar to the metastasis of malignant tumor. Some patients can be cured by radiotherapy, which is in line with the tumor theory.

2. There is immunoglobulin deposition in the capillary wall of allergic reaction or autoimmunity, and immune complexes appear in the serum of patients with active disease, which will disappear when the symptoms are relieved after treatment with immunosuppressant. Immunofluorescence test showed that there were C3 and LGG in the glomerular very basement membrane. Electron microscopy showed that there were coarse granules like immune complex in the basement membrane, and the ring immune complex increased; They are all autoimmune diseases.

3. The theory of bacterial and viral infection recently found that bacteria and viral bodies were found in the granuloma tissue for cell culture and in the patient's serum.

matters needing attention

For uncommon or unknown diseases, it's better to go to the hospital for examination, which is a responsible practice for both the patients and their families, so we must pay attention to it.