Treatment of myasthenia gravis

summary

My younger brother doesn't know what's wrong recently. He's always quarreling and tired. He wants to sleep and doesn't want to move at all. He doesn't know what's going on. Later, he went to the hospital. The doctor said that he had myasthenia gravis and treated him immediately. Now he's obviously better. Let's share the treatment of myasthenia gravis.

Treatment of myasthenia gravis

Treatment 1: myasthenia gravis is an autoimmune disease, cholinesterase inhibitors, glucocorticoids, immunoglobulin are commonly used in the treatment of drugs, related studies show that the use of glucocorticoid prednisone oral combined with intravenous immunoglobulin treatment of myasthenia gravis better.

Treatment 2: glucocorticoid has a wide range of regulatory effects on the immune system, and has become one of the main treatment methods in traditional treatment. However, long-term large-scale use of hormone has serious adverse reactions, especially in myasthenia gravis crisis, short-term high-dose pulse therapy can inhibit the release of presynaptic membrane acetylcholine, which may lead to the aggravation of myasthenia gravis. When respiratory muscle paralysis occurs, ventilator should be used.

Treatment 3: immunoglobulin can provide a large number of idiotypic antibodies, which can neutralize pathological autoantibodies and prevent them from acting on autoantigens; at the same time, it can reduce the production of autoantibodies; accelerate the degradation and metabolism of IgG antibodies; inhibit pathological cytokines; regulate the function of T cells and neutralize super antibodies, so as to reduce toxic T cells; and; It can compete or inhibit the binding of antibody circulating immune complex with autoantigen and enhance the inactivation of circulating immune complex. Nicotinic acetylcholine receptor (nAChR) is the antigen that causes autoimmune response in myasthenia gravis. Intravenous immunoglobulin therapy not only improves the clinical symptoms of myasthenia gravis, but also significantly reduces the blood titer of patients after treatment.

matters needing attention

I would also like to emphasize that: the pathogenesis of flaccidity is closely related to spleen qi deficiency. Therefore, diet regulation is more serious. We should not be too hungry or full. We should be thrifty and regular. At the same time, all kinds of nutrition should be properly allocated, and we should not be partial to food. On the basis of treatment, we should maintain an optimistic attitude towards life and confidence in rehabilitation, reduce the psychological burden, and do not use excessive brain and mental stimulation.