How is liver big spleen big to return a responsibility?

summary

The spleen is located in the left upper abdomen, which is the largest lymphoid organ and immune organ in the human body. If it can touch the lower edge of the spleen, it belongs to splenomegaly. Clinically, it can be judged by B-ultrasound or CT. Clinically, there are many causes of splenomegaly, including physiological and pathological reasons. The specific causes of splenomegaly need to be analyzed and judged according to the corresponding examination results. However, in general, what's the matter with hepatomegaly and splenomegaly? What about it? Let's take a look at it.

How is liver big spleen big to return a responsibility?

First, the spleen is the largest lymphoid organ in the human body, which has important functions such as blood storage, extramedullary hematopoiesis, destruction of blood cells, and participation in immunity. The spleen is not palpable under normal condition, and splenomegaly is also caused by pathological changes in other systems.

Second, the cause of splenomegaly in liver cirrhosis is that the circulation of liver is seriously damaged, and the blood return of portal vein system is blocked, which increases its pressure, forming an important pathological change of liver cirrhosis, namely "portal hypertension".

Third: due to the direct flow of splenic vein into portal vein, portal hypertension can block the return of splenic vein, hyperplasia of reticuloendothelial cells and fibrous tissue, and congestion of spleen, resulting in hyperemia and enlargement of spleen, and proliferative enlargement of spleen. This is the cause of cirrhosis and splenomegaly. In cirrhosis with splenomegaly, a large number of blood cells stay in the enlarged spleen and are destroyed by macrophages, resulting in a series of changes such as leukopenia, red blood cells, platelets and so on, which is called hypersplenism.

matters needing attention

We see the phenomenon of splenomegaly caused by some symptoms after the development of liver cirrhosis, so patients with liver cirrhosis should be treated in time, so as to effectively inhibit the development of the disease and avoid the occurrence of splenomegaly.