Is gastrointestinal stromal tumor easy to treat

Update Date: Source: Network

summary

Many people may not have heard of intestinal stromal tumor. The main symptom is stomachache. If you get this disease, you may not have any symptoms at the beginning, because once the disease is found, it has reached the advanced stage. Now let's popularize science for you, is it good to treat intestinal stromal tumor.

Is gastrointestinal stromal tumor easy to treat

First, gastrointestinal stromal tumor is a kind of tumor originated from gastrointestinal mesenchymal tissue, accounting for the majority of gastrointestinal mesenchymal tumors. Mazur proposed the concept of gastrointestinal stromal tumor for the first time in 1983. Gist is similar to interstitial cells of Cajal around gastrointestinal myenteric plexus, and all of them have positive expression of c-kit gene, CD117 (tyrosine kinase receptor) and CD34 (bone marrow stem cell antigen).

Second, there is no specific clinical manifestation. The course of disease can be as short as several days to 20 years. The course of disease of malignant GIST is relatively short, mostly within a few months. The main symptoms of GIST depend on the size and location of the tumor and are usually nonspecific. Gastrointestinal bleeding is the most common symptom. Dysphagia and dysphagia are also common in GIST. Some patients with perforated ulcer may increase the risk of abdominal implantation and local recurrence. The common symptoms are abdominal pain, mass and gastrointestinal bleeding and gastrointestinal obstruction. Ascites may appear in abdominal dissemination, and weight loss, fever and other symptoms may appear in malignant GIST.

Third: surgical resection: it is the first choice and the only possible cure method for gastrointestinal stromal tumors. Local resection or wedge-shaped resection is feasible. The distance between the cutting edge and the edge of the tumor should be more than 2cm. The recurrence and metastasis rate of GIST high-risk patients after operation is high, which can reach 55% - 90%. 80% of patients have local recurrence within 1-2 years after operation, and half of them have liver metastasis at the same time. Although it is possible to resect, it is difficult to improve the survival rate. The 5-year survival rate is 54% (50% - 65%) in patients with complete resection and no metastasis. The 5-year overall survival rate is less than 35% in patients with incomplete resection or metastasis From September to December.

matters needing attention

Intestinal stromal tumor is a branch of gastrointestinal stromal tumor, some people may be in a lot of abdominal pain, they can't judge which is what cause of abdominal pain, may delay treatment.