How to treat hyperprolactinemia?

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Hyperprolactinemia has a great impact on women. Hyperprolactinemia is a common disease in women, which brings a lot of harm to female friends. Hyperprolactinemia should be treated actively. How can I treat hyperprolactinemia? Let me tell you this.

How to treat hyperprolactinemia?

The first is to treat primary diseases such as pituitary tumor, hypothyroidism and Cushing's disease. Antiprolactin bromocriptine therapy bromocriptine is a semi synthetic ergot derivative, which is a dopamine receptor agonist. It can promote the synthesis and secretion of PRL IH, inhibit the synthesis and release of PRL, and directly act on pituitary tumor and PRL cells to inhibit tumor growth and inhibit the secretion of PRL, GH, TSH and ACTH. Bromocriptine therapy is suitable for all types of hPRL, and it is also the first choice for pituitary adenomas (micro / giant adenomas), especially for young infertile people who are looking forward to childbearing. The dosage was 2.5-7.5mg/d, orally. Other antiprolactin drugs include levodopa, cv205-502 and vitamin B6. See the anti prolactin section of endocrine therapy chapter for details.

Second, ovulation induction therapy is suitable for patients with hPRL, anovulatory infertility, and those who can't ovulate and get pregnant by bromocriptine alone. That is to say, bromocriptine combined with other ovulation inducing drugs should be used as a comprehensive therapy: ① bromocriptine CC hCG; ② Bromocriptine HMG hCG; ③gnrh。 Pulse therapy bromocriptine, etc. Comprehensive therapy can save antiprolactin, shorten treatment cycle and improve ovulation rate and pregnancy rate.

Third, surgical treatment is suitable for patients with giant adenoma with compression symptoms, and those who are ineffective in the treatment of anti-tumor drugs and bromocriptine, and who are suspected of secreting multiple pituitary hormones. The current trans sphenoidal microsurgery is safe, convenient and easy to operate, and its curative effect is similar to bromocriptine therapy. The combination of bromocriptine before and after operation can improve the curative effect. The disadvantages of the operation are: pituitary tumor without obvious capsule, unclear boundary, operation is not easy to complete or damage, resulting in cerebrospinal fluid nasal fistula, secondary pituitary dysfunction.

matters needing attention

. I hope you can pay attention to this disease. If you find signs of hyperprolactinemia, you must go to the hospital for diagnosis and active treatment.