What are the non hematopoietic cells in bone marrow?

summary

Due to the physiological variation and different investigation data, the cell ratio of each system of normal bone marrow picture has a large range of changes, so the actual meaning of normal bone marrow picture is normal range bone marrow picture, and the decline data can be used as the reference for the normal value of various blood cells in bone marrow smear: granulocyte system accounts for the largest proportion, about 1 / 2. In general, primordial granulocytes were less than 0.02, promyelocytes were less than 0.05, and neutrophilic rod-shaped nucleus was the most, its ratio was greater than that of lobulated nucleus cells, and it was also more than that of late promyelocytes, eosinophils were less than 0.05, basophils were less than 0.01. Let's share my experience with you.

What are the non hematopoietic cells in bone marrow?

The proportion of granulocyte system is the largest, about 1 / 2 strong. In general, primordial granulocytes were less than 0.02, promyelocytes were less than 0.05, and neutrophilic rod-shaped nucleus was the most, its ratio was greater than that of lobulated nucleus cells, and it was also more than that of late promyelocytes, eosinophils were less than 0.05, basophils were less than 0.01.

Red blood cell system accounted for the second place of bone marrow (nucleated red blood cells), accounting for about 1 / 5, most of which were late erythroblasts, followed by middle erythroblasts, primordial red blood cells < 0.01, early erythroblasts generally < 0.05, no megaloblasts. The percentage of lymphocytes is about 1 / 5, which is higher in children, sometimes up to 0.4, monocytes are generally less than 0.04, plasma cells are generally less than 0.015.

There is no unified method for megakaryocyte count. Generally, there are 7-35 megakaryocytes in the whole piece, among which the proportion of primitive megakaryocytes is 0-0.01, that of immature megakaryocytes is 0-0.05, that of granular megakaryocytes is 0.1-0.3, that of platelet producing megakaryocytes is 0.44-0.60, and that of naked megakaryocytes is 0.08-0.3. Because of the short residence time of platelet producing megakaryocytes in bone marrow, once platelets are produced, they will be released immediately. Therefore, in practical work, granulosa megakaryocytes are the main type of megakaryocytes in normal bone marrow, followed by naked megakaryocytes.

matters needing attention

Acute, chronic aplastic anemia and radiation sickness, reticular cells, plasma cells and tissue gel cells increased. Multiple myeloma with increased immature plasma cells. Malignant histiocytosis, reticular cells increased, in which more abnormal reticular cells can be seen. Sometimes there is a slight increase of reticular cells.