What is hypocalcemia
summary
As the name suggests, refers to the newborn baby's blood calcium content is too low, specifically lower than a what value is low? Hypocalcemia is defined as total serum calcium < 1.8 mmol / L or free calcium < 0.9 mmol / L. The degree of decrease is generally inversely proportional to the gestational age, but there is often a lack of signs. This is related to the factors of low plasma protein, acidosis, relatively high ratio of serum free calcium to total calcium. In early postnatal patients, the blood calcium is low and the blood phosphorus is abnormal or elevated, which may be accompanied by hypoglycemia; in late postnatal patients, the blood calcium is low and the blood phosphorus is high. What is hypocalcemia.
What is hypocalcemia
First: early hypocalcemia: occurs in the birth of self-esteem hours, common in low birth weight infants, thanks to a variety of difficult to give birth and intracranial hemorrhage, asphyxia, RDS, sepsis, hypoglycemia and other diseases in children; or after the application of alkaline solution to correct acidosis; or pregnant women with diabetes, pregnancy induced hypertension syndrome, prenatal bleeding, diet calcium and vitamin D deficiency and hyperparathyroidism According to the situation, the diagnosis and treatment of newborn infants are prone to hypocalcemia.
Second: late hypocalcemia: complex mainly occurs in artificially fed infants, due to the high phosphorus content in milk, soybean powder milk substitutes and cereals, and the low calcium / phosphorus ratio in milk, which is not conducive to the absorption of calcium, relatively high phosphate intake and relatively low renal corpuscle clearance recovery ability of newborns, leading to hyperphosphatemia and hypocalcemia. In addition, the deficiency of vitamin D intake during pregnancy, the use of sodium bicarbonate in the treatment of neonatal metabolic acidosis, or the use of sodium citrate as anticoagulant during exchange transfusion can reduce free calcium.
Third: other evaluation of hypocalcemia: it is common in infants with vitamin D deficiency or congenital hypoparathyroidism, and hypocalcemia lasts for a long time.
matters needing attention
Neonatal hypocalcemia needs to be treated under the guidance of doctors, and at the same time to closely observe the changes of the disease.