What examination does ichthyosis need to do

summary

After the birth of my child, I didn't pay much attention to the symptoms of ichthyosis, such as dry skin, covered with grayish white to light brown rhombic or polygonal scales, warped around and close to the skin in the center. But after 2 years, I still didn't get better. Ichthyosis was diagnosed in the hospital, and it was better after treatment. Let's take a look at the examination of ichthyosis.

What examination does ichthyosis need to do

First, we can observe the morphological characteristics of any part of the skin tissue, except the mucous membrane, whether the stratum corneum is significantly thickened and dense, and whether the hyperkeratosis around the hair follicles is significant. In the case of ichthyosis, dyskeratosis and positive hyperkeratosis can be seen especially in the toes. Dermal papilla can have inflammatory cell infiltration, and the diagnosis of this disease showed is very obvious.

Second: there is the loss or abnormality of granular layer observed by electron microscope, and the thin layer between granular layer and cuticle is missing, which can be easily observed in ichthyosis. There were dense lipid droplets and vacuoles in the cytoplasm of abnormal keratinocytes, especially in the palms and soles. Clear keratin granules can be absent, abnormal or normal.

Third: other examination methods include prenatal ultrasound, especially three-dimensional ultrasound, which can find some abnormalities related to fetal ichthyosis. The whole genome was extracted from the peripheral blood of the children, and the coding region of the gene was sequenced to find the mutation. This is also a more scientific detection method. After confirming the mutation of the proband, we can detect whether his relatives are carriers or not, and we can also make prenatal diagnosis for the fetus. Finally, the vital signs of newborns were monitored and routine serological examination was carried out. So we can make a diagnosis.

matters needing attention

Here I would like to remind you that daily bathing is also a way of maintenance. Patients with ichthyosis can take hot spring bath and apply health preserving skin care oils to make skin soft, reduce scales and itching of ichthyosis, prevent skin from being too dry, and prohibit alkaline soap and irritant drugs.