What is Stevens Johnson syndrome?

summary

As a severe type of erythema multiforme, it is listed as erythema multiforme. There are bullae on the skin, typical or atypical target damage and extensive mucosal damage, accompanied by fever, visceral damage and other systemic symptoms. Most of them are 20-40 years old. What is Stevens Johnson syndrome? Next, I'd like to share my views with you.

What is Stevens Johnson syndrome?

The prodromal symptoms were nonspecific upper respiratory tract infection, accompanied by fever, sore throat, chills, headache, arthralgia, vomiting, diarrhea and weakness. The skin and mucous membrane damage suddenly appeared. The rash was pleomorphic, including erythema, papule, wheal, blister, bulla and purpura.

The lesions are distributed in all parts of the body, including palms, plantars, dorsum of hands and extensors of limbs, and often involve the trunk and face. Mucosal damage is extensive and serious, in addition to involving the oral cavity, eyes, perianal and vulva, but also involved in the nose, throat and respiratory tract, digestive tract, urogenital tract mucosa.

The disease is a systemic disease, which can involve internal organs and cause corresponding symptoms. Hematuria and proteinuria may occur in renal damage, and tubular necrosis and renal failure may occur in severe cases; In patients with liver damage, the level of aminotransferase increased, but also lymph node enlargement, tachycardia, hypotension, seizures and disturbance of consciousness.

matters needing attention

All kinds of inducing factors should be avoided, such as not taking drugs at will, especially those who have been allergic to the same kind of drugs, should avoid using them again. Prevention and treatment of various infections.