Symptoms of vitamin D poisoning in infants?

summary

Vitamin D poisoning is one of the iatrogenic diseases. It is mainly due to the misdiagnosis and excessive use of vitamin D preparations in the prevention and treatment of rickets, such as cod liver oil, vitamin D2 (ossitol), vitamin D2 (cholecalciferol or choleretin) and vitamin D colloidal calcium. Symptoms of vitamin D poisoning in infants? Let's talk about it.

Symptoms of vitamin D poisoning in infants?

The earliest symptom is loss of appetite, even anorexia, irritability, crying, low spirit, more low fever. There may also be hyperhidrosis, nausea, vomiting, diarrhea or constipation, gradual emergence of thirst, frequent urination, nocturia, occasional dehydration and acidosis.

Older children can report headache, blood pressure can rise or fall, heart can be heard and systolic murmur, ECG ST segment can rise, sometimes mild anemia. Severe cases may appear depression, hypotonia, dyskinesia, even coma, convulsion, renal failure, etc. Urine specific gravity is low and fixed, urine protein is positive, cell increases, also can have tubular.

Long term chronic poisoning can lead to calcification of bones, kidneys, blood vessels and skin, affect physical and intellectual development, and even cause death due to renal failure. Vitamin D poisoning in early pregnancy can cause fetal malformation.

matters needing attention

1. After the diagnosis of vitamin D poisoning, stop VitD preparation and calcium immediately, avoid sunlight and give low calcium diet. 2. Control infection and correct dehydration acidosis. In general, it takes a long time for the patients to recover after the above treatment. The blood calcium level will return to normal after 2-3 months, and the recovery of renal function can be delayed for 18 months. 3. Specific therapy: adrenocortical hormone can inhibit intestinal absorption of calcium, and has antagonistic effect with VitD. Oral prednisone 1-2 mg / kg / D, 1-2 weeks after the blood calcium returned to normal, generally stopped taking 2-3 weeks, blood calcium did not rise. According to the blood calcium and X-ray picture, the medication time can be prolonged in severe cases. Oral administration of sulphuric acid can reduce the absorption of calcium, 1-2g for older children.