Psoriasis is caused by those reasons

summary

Psoriasis, like his name, is very difficult to treat. At the same time, it is easy to relapse after treatment. It is very difficult to treat it thoroughly. At the same time, it also causes great damage to the skin, causes bad personal image, and may lead to abnormal work. What are the reasons for this disease? How do we prevent it, All we need to know.

Psoriasis is caused by those reasons

1. Infection: is one of the important causes of psoriasis, especially in children. According to reports, psoriasis patients, suffering from chronic tonsillitis accounted for more than 90%, followed by acute tonsillitis in patients with psoriasis accounted for 49.5%, children with psoriasis patients often accompanied by upper respiratory tract infection and tonsillitis, psoriasis patients infected by Streptococcus can quickly worsen, the application of antibiotics after the treatment of psoriasis can often reduce, visible upper respiratory tract infection and tonsillitis There is a certain relationship between systemic inflammation and psoriasis, which may be an allergic reaction to bacterial toxins.

2. Immune function disorder. Immunological studies have confirmed that the humoral immunity of patients with psoriasis is in disorder. T suppressor cells in the blood of patients are significantly decreased, T helper cells are increased, cellular immune function is low, lymphocyte transformation rate and natural petal formation rate are reduced, and skin delayed hypersensitivity test is weakened. It is also reported that T cells are mainly infiltrating cells in the lesions of psoriasis, which is the main reason The expression of HLA DR and LL-2 receptor on the surface of some cells can secrete some cytokines, which can cause a series of metabolic abnormalities in keratinocytes in the lesion area and lead to the occurrence of psoriasis.

3. Metabolic disorder, the important pathophysiological change of psoriasis is the acceleration of epidermal cell proliferation, which shortens the replacement time of epidermal cells. The replacement time of normal epidermal cells is 26-28 days, while the replacement time of psoriasis lesions is 3-4 days. Therefore, the maturation of epidermal cells is interfered, leading to the disorder of epidermal histology, seriation and keratosis, resulting in a series of diseases such as silvery white scales It is a phenomenon of reason. The rapid growth of epidermal cells in psoriasis may be related to the direct action of a substance called "polyamine", which is an important regulatory substance in cell biology, especially in the treatment of psoriasis dna.rna Due to a variety of biochemical reasons, polyamine synthesis and its concentration increase. Polyamines combine with nucleic acid and protein in cells, and accelerate enzyme reaction It can accelerate cell division and shorten the time of cell replacement, which leads to some pathological changes of psoriasis.

matters needing attention

For the pathogenesis of psoriasis disease has been understood, I hope that through these understanding we can have an understanding of how to prevent psoriasis, because this skin disease is very difficult to treat, so we all have to start from prevention, which is the most effective way to reduce skin damage.