Why is interstitial nephritis creatinine high?

summary

Interstitial nephritis, also known as tubulointerstitial nephritis, and many people have known about its basic treatment, is a clinicopathological syndrome of acute and chronic renal tubulointerstitial damage caused by various reasons. Clinical often divided into acute interstitial nephritis, chronic interstitial nephritis. Acute interstitial nephritis is characterized by interstitial inflammatory cell infiltration, interstitial edema, varying degrees of renal tubular damage and renal insufficiency in a short time due to a variety of reasons. In order to avoid this situation, let's talk about why the creatinine of interstitial nephritis is high?.

Why is interstitial nephritis creatinine high?

First, pathogenic infections include bacteria, fungi and viruses, including Staphylococcus aureus septicemia, severe Streptococcus infection, diphtheria, fishy red fever, mycoplasma pneumonia, syphilis, brucellosis, legionellosis, hepatitis B virus antigenemia, cytomegalovirus infection, typhoid fever, measles, pyelonephritis, etc.

Second: systemic diseases such as systemic lupus erythematosus, Sjogren's syndrome, sarcoidosis, primary cryoglobulinemia. Hematological diseases, such as multiple myeloma, paroxysmal hemoglobinuria, lymphoproliferative diseases, sickle cell disease, etc.

Third, the long-term use of cyclosporine, aminoglycoside antibiotics, amphotericin B, analgesics, non steroidal anti-inflammatory drugs and cisplatin may be related to the drug pathogenesis.

matters needing attention

1. The first step in the treatment of interstitial nephritis is to remove the etiology, control the infection, stop the use of sensitizing drugs in time and deal with the primary disease. 2. Symptomatic support treatment to correct renal anemia, electrolyte, acid-base and volume imbalance, serum creatinine significantly increased or combined with hyperkalemia, heart failure, pulmonary edema and other indications of blood purification, clinical blood purification should be carried out in time, acute interstitial nephritis can choose continuous blood purification treatment. If the condition permits, renal transplantation is feasible for patients with uremia.