Symptoms of liver injury after taking tuberculosis drugs

summary

Tuberculosis is a very common chronic infectious disease, which can be transmitted between human and livestock. It is caused by Mycobacterium tuberculosis infection. Antituberculosis drugs generally refer to all the drugs that can treat tuberculosis, there are 11 kinds at present. Common anti tuberculosis drugs include isoniazid, rifampicin, pyrazinamide, sodium p-aminosalicylate, etc. Although these drugs have certain therapeutic effect on tuberculosis, they are also easy to cause adverse reactions. The main adverse reactions caused by antituberculosis drugs are gastrointestinal reactions, liver damage, joint damage and so on. Among them, liver damage is the most common symptom. Let's understand the adverse reactions of antituberculosis drugs.

Symptoms of liver injury after taking tuberculosis drugs

Adverse reactions of antituberculosis drugs. The main adverse reactions caused by anti tuberculosis drugs are gastrointestinal reactions, liver damage, joint damage, etc. Among them, the incidence of gastrointestinal reactions is the highest, and liver damage is the most important, other adverse reactions are rare. In the past, if liver injury occurred, we would consider stopping the drug first, but now we think it is not necessary to stop the drug. At the beginning of taking medicine, the patient may have the phenomenon of single transaminase rising. If the single transaminase is mild to moderate, or the elevation lasts for more than two weeks, patients can take liver protection tablets, Glucurolactone and other liver protection drugs.

Treatment of adverse reactions. If the patient has toxic liver damage, vitamin K can be supplemented appropriately. If the patient has the problem of low fibrinogen content, in addition to vitamin K, fresh plasma can also be injected. If the patient's transaminase increased seriously, and jaundice, it is best to stop taking drugs. If hypoproteinemia occurs, albumin should be supplemented.

Tuberculosis is caused by tuberculosis infection, is a chronic infectious disease, known as "white plague", can be widely spread. At present, there are 11 kinds of antituberculosis drugs, including isoniazid, rifampicin, pyrazinamide, sodium p-aminosalicylate, ethambutol, etc. The adverse reactions of antituberculosis drugs to human body include gastrointestinal reaction, liver damage, joint damage, nervous system reaction and so on.

matters needing attention

This paper introduces the symptoms and treatment of liver damage caused by taking anti tuberculosis drugs. Most of the anti tuberculosis drugs have side effects and adverse reactions, which have a great impact on the body. Anti tuberculosis drugs can be divided into two categories, first-line drugs and second-line drugs. The first-line drugs are characterized by good effect and low toxicity, while the second-line drugs are characterized by poor efficacy and high toxicity. We must choose the right medicine according to the patient's condition.