What is connective tissue disease

summary

Connective tissue disease is not a single disease, but a general term, such as rheumatoid arthritis, lupus erythematosus is a typical example, the disease is more complex. Let's see what connective tissue disease is.

What is connective tissue disease

First of all, connective tissue disease refers to connective tissue involvement, including lupus erythematosus, rheumatoid arthritis, scleroderma, dermatomyositis, polyarteritis nodosa, Wegener granuloma, giant cell arteritis and Sjogren's syndrome. According to the classification of rheumatism revised by American rheumatic society in 1982, connective tissue diseases can also include allergic vasculitis, Behcet syndrome, nodular non suppurative febrile panniculitis, etc. Connective tissue disease has some common clinical, pathological and immunological features, such as multiple system involvement (skin, joint, muscle, heart, kidney, hematopoietic system, central nervous system, etc.) with long course and complex condition, accompanied by fever, arthralgia, vasculitis, increased erythrocyte sedimentation rate, increased gamma globulin, etc.

Secondly, the etiology of the disease is not very clear. It is generally considered to be related to heredity, immune abnormality and virus infection. With the development of immunology, it is found that most connective tissue diseases are accompanied with immunological abnormalities, such as low function of suppressive T cells, high humoral immune function, and most connective tissue diseases have autoantibodies. Therefore, these diseases are also classified as autoimmune diseases.

Finally: connective tissue disease has some common clinical, pathological and immunological features, such as multiple system involvement (i.e. skin, joint, muscle, heart, kidney, hematopoietic system, central nervous system can be involved at the same time), long course of disease, complex condition, accompanied by fever, arthralgia, vasculitis, increased erythrocyte sedimentation rate, increased gamma globulin, etc.; but each has its own characteristics. After the disease, according to the condition of treatment, is the key to the treatment of this disease.

matters needing attention

Connective tissue disease includes many diseases, all have their own characteristics, once there is a similar situation, to actively treat, according to the disease can get the best effect.