What harm does inclusion body myositis have?

summary

Inclusion body myositis is an inflammatory myopathy characterized by the appearance of rimmed vacuoles under the light microscope or in the center of the muscle fiber, and the appearance of tubulofilamentous inclusion bodies in the muscle substance or muscle nucleus under the electron microscope. The course of the disease is slow, and the affected muscles have specific parts, which may be related to immune-mediated. What is the harm of inclusion body myositis? Let's talk about it

What harm does inclusion body myositis have?

The selective muscle weakness of flexor pollicis longus is the most characteristic. About 1 / 3 of the patients had facial weakness and most of the extraocular muscles were not involved. Due to the involvement of pharyngopharyngeal muscles, many patients may have dysphagia.

Physical examination showed atrophy of palm forearm muscle group and quadriceps femoris with disappearance of knee reflex. Other tendon reflex was normal initially, but it could be weakened with the progress of the disease. A few patients may have cardiovascular disease.

It is often insidious onset and chronic progression, mainly manifested as painless myasthenia and muscle atrophy. Proximal or distal muscle groups can be involved, especially quadriceps femoris. The patient developed unilateral or bilateral local muscle weakness, such as quadriceps femoris, flexor digitorum, flexor carpi or flexor dorsalis pedis,

matters needing attention

At present, there is no specific treatment, such as the rapid development of the disease, and pathological indications of inflammatory cell infiltration, can try glucocorticoid and immunosuppressant treatment, also can use large doses of immunoglobulin intravenous drip treatment, has a certain effect.