Systemic lupus erythematosus symptoms?

Update Date: 2022-02-27 Source: Network

summary

Speaking of rheumatic immune diseases, the most frequently mentioned should be rheumatoid arthritis and systemic lupus erythematosus. As a chronic autoimmune disease with multiple system damage, systemic lupus erythematosus is different according to the location and degree of the affected organs, and the severity of the disease. So systemic lupus erythematosus symptoms? Let's talk about it

Systemic lupus erythematosus symptoms?

There are various manifestations, which can be divided into specific and non-specific. ① The specific lesions were butterfly erythema, subacute cutaneous lupus erythematosus and discoid erythema. ② Nonspecific skin lesions include photoallergy, alopecia, oral ulcer, skin vasculitis (purpura), pigmentation change (pigmentation or loss), reticular green spot, Raynaud's phenomenon, urticaria like rash, rare lupus panniculitis or deep lupus erythematosus and bullous lupus erythematosus.

The manifestations included arthralgia, arthritis, joint deformity (10% X-ray damage), myalgia, myasthenia, avascular osteonecrosis and osteoporosis. Pericarditis (4% of the patients had signs of pericardial tamponade) and myocarditis mainly manifested as congestive heart failure and heart valve disease, such as Libman sacks endocarditis. Coronary arteritis is rare, mainly manifested as chest pain, abnormal ECG and elevated myocardial enzymes.

The main manifestations of pleurisy, pleural effusion and lung contraction syndrome were suffocation and diaphragmatic dysfunction; Pulmonary interstitial disease, pulmonary embolism, pulmonary hemorrhage and pulmonary hypertension can occur.

matters needing attention

Chloroquine or hydroxychloroquine is effective for patients with rash, low fever, arthritis, mild pleurisy and pericarditis, mild anemia, leukopenia and Sjogren's syndrome. Long term application is helpful to reduce hormone dosage and maintain remission. The main adverse reactions were cardiac conduction disorder and retinal pigmentation. ECG and ophthalmic examination should be performed regularly.