Symptoms of hypercalcemia?

summary

Hypercalcemia refers to the abnormal increase of serum ionic calcium concentration. Because the determination is usually total calcium, rather than ionic calcium, we must pay attention to the factors affecting ionic calcium. Serum albumin concentration is the most important factor in clinic, because albumin is the main calcium binding protein in blood circulation. Symptoms of hypercalcemia? Let's talk about it

Symptoms of hypercalcemia?

The light ones are weak, tired and indifferent; Severe patients have headache, muscle weakness, weakened tendon reflex, depression, irritability, gait instability, language disorders, hearing, vision and orientation disorders or loss, numbness, behavioral abnormalities and other mental and neurological symptoms. Delirium, convulsion and coma may appear in hypercalcemia crisis. Neuropsychiatric symptoms are mainly caused by the toxicity of high calcium to brain cells, which can interfere with the electrophysiological activities of brain cells.

May cause the blood pressure to rise and each kind of arrhythmia. ECG showed Q-T interval shortening, ST-T changes, atrioventricular block and hypokalemic U wave. If not treated in time, it can cause fatal arrhythmia. Hypercalcemia can lead to increased renal micturition and electrolyte disorder, thickening of bronchial secretions, weakening of ciliary activity of mucosal cells, and poor drainage of bronchial secretions, which can easily lead to pulmonary infection, dyspnea, and even respiratory failure.

The symptoms were anorexia, nausea, vomiting, abdominal pain, constipation, and paralytic ileus in severe cases. Calcium can stimulate the secretion of gastrin and gastric acid, so patients with hypercalcemia are prone to peptic ulcer. The ectopic deposition of calcium in pancreatic duct and the stimulation of pancreatic enzyme secretion by calcium can lead to acute pancreatitis.

matters needing attention

Intravenous rehydration to increase extracellular volume, followed by sodium diuretics, such as diuretic sodium, furosemide, can increase the excretion of urine sodium, then the excretion of urine calcium is also increased, so as to correct hypercalcemia. However, there are contraindications for patients with renal insufficiency and congestive heart failure.