How is blood phosphorus on the high side to return a responsibility

summary

Most people don't know about the high level of blood phosphorus, and few people encounter it, but we still need to understand that in normal people, parathyroid hormone and calcitonin inhibit the reabsorption of phosphorus in renal tubules, and they play an antagonistic role in the regulation of calcium and phosphorus metabolism in intestine, bone and kidney, so blood phosphorus is maintained at a normal level and is not easy to rise. However, it can occur in renal failure, hypoparathyroidism, phosphorus transfer into the blood after cell damage, excessive vitamin D and excessive intake.

How is blood phosphorus on the high side to return a responsibility

First, renal failure is difficult to discharge phosphorus: the glomerular filtration rate is reduced to less than 30ml/min * and blood phosphorus is increased, often accompanied by azemia or uremia and acidosis.

Second: hypoparathyroidism: urinary phosphorus absorption increased, blood phosphorus often increased and blood calcium decreased.

Third: phosphorus transfer into blood after cell damage: it can be seen in metabolic acidosis caused by cell damage caused by various reasons, such as high fever and poisoning. It is often accompanied by hypermetabolism and disintegration of cell catabolism. In a variety of malignant tumors, especially lymphoma and leukemia, phosphorus escapes into blood circulation due to cell disintegration during chemotherapy.

matters needing attention

Excessive intake and intestinal absorption: it occurs when infants are fed with milk, because the content of phosphorus and calcium in milk is much higher than that in human milk (milk contains 940mg / L phosphorus and 1220mg / L calcium); Human milk contains only 150 mg / L of phosphorus and 340 mg / L of calcium, so the blood phosphorus of infants can reach 2.3 mmol / L. When adults take potassium phosphate or vitamin D orally, they also get sick due to excessive absorption.