Pulmonary tuberculosis after liver damage symptoms?

summary

Tuberculosis is a relatively common disease, in China is a high incidence area, tuberculosis is mainly caused by human infection of Mycobacterium tuberculosis, before tuberculosis is a terminal disease, it is impossible to treat, now with the development of medicine has been studied out of anti tuberculosis drugs, tuberculosis symptoms after liver damage? Next, I'd like to share my views with you.

Pulmonary tuberculosis after liver damage symptoms?

The drug has direct damage to the liver. For example, INH reacts with acetyl group to synthesize acetyl isoniazid in liver by N-acetyltransferase, and then acetyl isoniazid is hydrolyzed to acetyl hydrazine with stronger toxicity in liver, which is transformed into reaction medium by microsomal enzyme in liver cells,

And then combined with cell protein, leading to hepatocyte degeneration and necrosis. It can also induce lipid peroxidation and cause drug-induced hepatitis.

Indirect liver damage. The drug itself and its metabolites interfere with or block the liver cells and an important metabolic pathway or bile excretion function, resulting in liver cell injury or bile excretion disorder. RFP is a macromolecular drug, which is mainly excreted through bile. The concentration of RFP in bile is 2000 times higher than that in plasma,

matters needing attention

Most of the patients with pulmonary tuberculosis are thin, so it's better to supplement some high protein and high nutrition food in the normal diet. Most of the patients have poor immunity, so it's better to inject some globulin into the patients,