Infantile spasm, how to return a responsibility?

summary

In this era of family planning, children are getting more and more attention from parents. Once there are any symptoms of discomfort, parents will immediately take their children to the hospital for examination. For newborn infants, their immunity is relatively low, easy to suffer from a variety of diseases, infantile spasm is one of them. Because the baby is in bed all day and the young mother has no experience of taking care of the baby, the possibility of suffering from infantile spasm is increased. What's the matter with this disease? Let's learn about it!

Infantile spasm, how to return a responsibility?

First, due to the progress of diagnosis and treatment technology, finding the cause of the disease is increasing. Cryptogenic infantile spasm (10% - 15%) is of unknown etiology, without other signs of central nervous system dysfunction. Symptomatic infantile spasm (85% - 90%) is characterized by previous signs of brain damage or definite etiology. The most common etiology (78%) is cerebral ischemia and hypoxia, brain hypoplasia, intrauterine infection, brain malformation and congenital metabolic disorders. The most common causes are infection, brain hypoxia and head injury. 73% of the 71 children with this disease were found to be abnormal, including brain atrophy (49%), congenital abnormality (18%) and hydrocephalus (6%). Brain malformation and calcification were also reported. More than 20% of patients with tuberous sclerosis developed this disease. In recent years, congenital cytomegalovirus infection, Toxoplasma infection, rubella, herpes simplex can cause the disease. The etiology of 146 cases of this disease was analyzed in our country and our ancestors. 26% of them were primary, and the rest were symptomatic, including phenylketonuria, microcephalus, cerebral palsy, Down's syndrome and macrocephaly, congenital brain hypoplasia; Intrapartum factors included intrauterine asphyxia, intrapartum injury; Postnatal factors include infectious diseases combined with encephalopathy, encephalitis, meningitis and brain trauma, vaccine injection, etc.

Second: in clinical treatment, we should pay attention to protect the fetus and newborn from hypoxia, birth injury, infection and other damage, but also to protect the risk of fetal asphyxia. If you are pregnant, you should do more prenatal examination, and check the fetus, and then decide the necessity of pregnancy and early treatment. Pay more attention to the health of the fetus, pay attention to whether the fetus has abnormal mental state. Prevent the possibility of infantile spasm.

Third: antiepileptic drugs can be used to treat infantile spasm in clinic. The commonly used drugs in clinic are nitrazepam, clonazepam, sodium propionate and other drugs. However, this kind of drugs should not be combined with corticosteroids, otherwise antagonistic effect will occur. High dose vitamin B6 is also an adjuvant treatment for infantile epilepsy. Moreover, the coenzyme of glutamate decarboxylase can inhibit the excitability of receptor and block the synaptic conduction of ganglion. 　　

matters needing attention

1. The fetus should pay attention to protect the fetus and newborn from hypoxia or infection. 2. Pregnant women should actively prevent and treat febrile convulsion, and take medication immediately when it occurs. 3. We should also actively prevent children's nervous system diseases, if found, we should treat them in time, so as to reduce the sequelae.