Relapse after leukaemia bone marrow transplants how to return a responsibility
summary
Some time ago, I went to the welfare home with my friends to see those children with leukemia. I was very emotional. At the same time, I have a deeper understanding of leukemia. Today, let me talk about the relapse of leukemia after bone marrow transplantation.
Relapse after leukaemia bone marrow transplants how to return a responsibility
First, relapse after bone marrow transplantation is one of the important factors affecting the curative effect of bone marrow transplantation. It reduces the long-term survival rate of bone marrow transplantation in the treatment of leukemia, and is a major problem endangering the life of patients after bone marrow transplantation. The relapse rate of leukemia after allogeneic bone marrow transplantation is about 20% - 30%.
Second, the main reason for relapse of leukemia is the incomplete clearance of leukemia cells during bone marrow transplantation. That is to say, there are many residual leukemia cells in the body, which is related to the weak anti leukemia effect of bone marrow transplantation. At present, through the detection of minimal residual disease after bone marrow transplantation, the research of leukemia recurrence prediction is being explored.
Third: in the treatment of relapse of leukemia after bone marrow transplantation, for acute leukemia, we generally strive to induce remission again through chemotherapy, and then carry out the second bone marrow transplantation. For some cases, we can also directly carry out the second bone marrow transplantation without inducing remission. For the patients with poor general condition who can not tolerate the second bone marrow transplantation, only supportive treatment and symptomatic treatment can be done.
matters needing attention
After the first bone marrow transplantation, we should pay attention to rest, pay more attention to the emergence of postoperative symptoms, prevent the possibility of secondary recurrence, and strictly follow the doctor's advice in diet and physical exercise.