Why clonidine is used in growth hormone challenge test?

summary

Growth hormone stimulation test growth hormone stimulation test is to use arginine hydrochloride to stimulate the secretion of growth hormone to judge whether the reserve function of growth hormone is normal. Why clonidine is used in growth hormone challenge test?

Why clonidine is used in growth hormone challenge test?

The peak value of growth hormone was less than 7 μ G / L, commonly used in the diagnosis of dwarfism and dwarfism. Abnormal results: Patients with short stature and dwarfism need to be examined because of insufficient growth hormone reserve caused by pathological changes.

Unsuitable population: arginine should be used with caution in patients with severe liver and kidney diseases or diabetes mellitus complicated with acidosis. Check before taboo: pay attention to normal diet, pay attention to normal work and rest, prevent endocrine disorders. After 8 pm, fasting overnight, the next morning in bed. Blood samples were taken to check the basic growth hormone. Inspection requirements: actively cooperate with the doctor's requirements. If the solution leaks subcutaneously during injection, it may cause redness, swelling and pain reaction of local tissue and should be avoided.

Methods: ① fasting overnight after 8 p.m. and lying in bed in the morning. Blood samples were taken to check the basic growth hormone. (2) arginine hydrochloride 0.5g/kg body weight, diluted to 200ml with water for injection, and dripped within 30 minutes. (3) at 30, 60, 90 and 120 minutes after infusion, blood samples were taken from the other upper limb to measure growth hormone.

matters needing attention

Related diseases, acromegalic cardiomyopathy, Sheehan syndrome, gigantism and acromegaly, idiopathic puberty delay, pituitary dwarfism, growth hormone deficiency, omphalocele megaglossia megasyndrome. Related symptoms, abnormal short stature, dwarfism at birth