Pathogenesis of psoriasis

summary

Psoriasis is a common skin disease, but it is difficult to treat psoriasis. My cousin suffered from psoriasis. She had several white plaques on her arm. Recently, she went to the hospital for treatment. The doctor also told us the cause of psoriasis.

Pathogenesis of psoriasis

Cause 1: it is generally believed that the disease is autosomal dominant inheritance with incomplete penetrance. It is reported that 10% - 23.8% of the patients have family history in China. The prevalence rate of family disease is much higher than that of the general population.

The second cause of disease: bacterial infection is also one of the causes of disease. Streptococcus is the most likely bacteria to cause our disease, and this kind of bacteria is everywhere in our daily life. It is impossible for us to completely avoid it. The best thing is to increase the resistance of the body to bacteria, so that bacteria can not invade the body.

Cause 3: it has been found that the keratin extract of psoriasis vulgaris and pustular psoriasis contains complement component C3a, which can make neutrophils aggregate to the lesion and form micro abscess. T lymphocyte infiltration exists in the dermis of psoriasis. Activated T lymphocytes release cytokines to stimulate the proliferation of keratinocytes.

matters needing attention

Psoriasis patients must avoid contact with spicy food, timely relieve the pressure of life, daily life because of work pressure, mental stress, can attack a series of psychological or physiological reactions, promote neuroendocrine disorders, harm the body's immune protection system, and some enzyme metabolic disorders, and then promote the attack of psoriasis.