Azathioprine in myasthenia gravis

summary

Recently, I always feel that I have no strength all over. At first, I thought I had a cold, but I still didn't get well after taking cold medicine. Then I went to the hospital for examination. The doctor said that I had myasthenia gravis, and I had treatment immediately. Now I'm obviously better. Let's share the myasthenia gravis azathioprine.

Azathioprine in myasthenia gravis

Treatment 1: anticholinesterase drugs such as pyridostigmine 60-360 mg / time, 3-5 times / day, neostigmine bromide 15-90 mg / time, 3-5 times / day. Patients with slow heart rate, arrhythmia, mechanical intestinal obstruction and asthma should not use it or use it with caution.

Treatment 2: polarizing solution (10% glucose 250-500 ml, 10% potassium chloride 10-15 ml, insulin 8-16 units), neostigmine 0.5-2.0 mg, dexamethasone 5-15 mg, intravenous drip once a day, 10-12 times as a course of treatment. One course of treatment was repeated intermittently for 5-7 days. Generally, 2-3 courses of treatment showed marked effect. Polarized solution could restore the function of endplate and the metabolic function of acetylcholine cholinesterase system. Calcium can also be taken orally or intravenously. Calcium not only plays an important role in the process of nerve transmission. It can also enhance the secretion of acetylcholine.

Treatment 3: immunosuppressive agents were used according to the immune function: ① prednisone 45-80 mg / day, lasting for 3-5 months. ② Cyclophosphamide 200 mg IV, together with VitB 6100-200 mg, added to 250 ml of 10% glucose, once a day, 10 times as a course of treatment; or 50 mg orally, 2-3 times a day. ③ Azathioprine 25-50 mg orally, 2-3 times a day, and can be combined with prednisone for a long time. In addition, cyclosporine (6 mg / kg / day) can also be used for treatment.

matters needing attention

For this kind of disease: dampness heat immersion myasthenia gravis treatment: dampness heat evil damage guanidine spleen and stomach, transport can not, dampness from endogenous, immersed in the veins, the road is not good, affect the operation of Qi and blood and Rong Yang, resulting in muscle flaccidity. The treatment principle of myasthenia gravis: clearing heat and removing dampness, drying and warming phlegm.